ChemSystemsChem

Function in RNA oligomers - specifically low μM specific binding of purine (ATP and GTP) nucleotides - can arise from single, non-functional and partially homopolymeric (polyA) sequences of minimal structural and informational complexity by iterativ...

Freeze-thaw cycles serve as physicochemical driving force for the lateral exchange of enclosed material between giant lipid vesicles. It was demonstrated that this exchange relies on transient periods of membrane permeability leading to content diff...

Glass composition matters: This work demonstrates that the outcome of dry-phase prebiotic polymerization reactions could have been strongly affected by the oxide composition of the hosting rock glasses. Abstract Silicate glasses are ubiquitous on ...

The Front Cover illustrates the exchange of genetic material between model protocells through cycles of freezing and thawing. Freeze-thaw cycles as prebiotic environmental driver induce a transient increase in membrane permeability enabling the late...

The recognition of carbohydrates has been of growing interest in the supramolecular chemistry field, with specific relevance for numerous potential applications. At the same time, the binding many of carbohydrates in water selectively and with high ...

Building communicating synthetic cells using droplet interface bilayers encapsulating cell-free expression systems with quorum sensing gene circuits. Abstract Building synthetic multicellular systems using non-living molecular components is a gran...

Dynamic combinatorial library of peptides can be generated either through amino-acid like monomers oligomerization, amino-acid side-chain grafting on static scaffolds or pre-synthesized peptide assembly. These stimuli responsive libraries are of gre...

A three-component molecular ensemble consisting of a constitutionally dynamic cage, a rotaxane and a luminophore acts as a signal transducer which assimilates three input signals, i. e., Zn²⁺, H⁺, and Cu⁺, to perform two individual logic operations....