The strategic application of non-covalent interactions has emerged as an innovative paradigm in carbohydrate chemistry. Herein, we described a thiocyanato-enhanced neutral monodentate halogen bonding donor demonstrating high efficacy in convertin...
Artikel
Synthesis of Multisubstituted Pyranoindol‐1‐ones Using Iridium‐Catalyzed Intramolecular C─H Amination of 3‐Amino‐4‐phenyl‐2‐pyrones
Asian Journal of Organic Chemistry, August 2025, DOI. Login für Volltextzugriff.
Von Wiley-VCH zur Verfügung gestellt
A method for the synthesis of multisubstituted pyranoindol-1-ones is developed, utilizing iridium-catalyzed intramolecular C─H amination of 3-amino-4-phenyl-2-pyrones synthesized via the conjugate addition of diethyl 2-aminomalonate to alkynyl ketones. This synthetic strategy was successfully applied to the synthesis of analogues of biologically active compounds.
Abstract
A method for the synthesis of multisubstituted pyranoindol-1-ones is developed, utilizing iridium-catalyzed intramolecular C─H amination of 3-amino-4-phenyl-2-pyrones synthesized via the conjugate addition of diethyl 2-aminomalonate to alkynyl ketones. This synthetic strategy was successfully applied to the synthesis of analogues of biologically active compounds.
Zum VolltextÜberprüfung Ihres Anmeldestatus ...
Wenn Sie ein registrierter Benutzer sind, zeigen wir in Kürze den vollständigen Artikel.