<p>Photoredox catalysis has become a mainstay in synthetic methodology over the past decade. However, its versatility for the development and functionalization of natural products remains further exploration. Herein, we report an efficient approach to synthesize artemisinin G by using TBADT as the efficient initiator under mild conditions.</p>

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Synthesis of Artemisinin G from Artemisinin via Photocatalysis

Photoredox catalysis has become a mainstay in synthetic methodology over the past decade. However, its versatility for the development and functionalization of natural products remains further exploration. Herein, we report an efficient approach to synthesize artemisinin G by using TBADT as the e...

<p>An efficient N-heterocyclic carbene (NHC)-catalyzed kinetic resolution of 2-substituted 3-nitro-1,2-dihydroquinolines (DHQs) allowing the synthesis of densely functionalized enantioenriched tetrahydroquinolines through the resolution at remote stereocenter is described. The Re-face addition of α,β-unsaturated  azolium homoenolate intermediate generated in situ from enal with the more kinetically favored (S)-enantiomer of the racemic 2-substituted 3-nitro-1,2-dihydroquinolines (rac-1), affording the enantiopure tetrahydroquinolines (up to &gt;99:1 dr, &gt;99:1 er) and the opposite (R)-enantiomer of DHQ (ent-1) was recovered (up to &gt;99:1 er).</p>

N‐Heterocyclic Carbene–Catalyzed Kinetic Resolution of 3–Nitro–1,2–dihydroquinolines: Asymmetric Synthesis of All C2–, C3– and C4–Functionalized Tetrahydroquinolines

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Synthesis of Artemisinin G from Artemisinin via Photocatalysis

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N‐Heterocyclic Carbene–Catalyzed Kinetic Resolution of 3–Nitro–1,2–dihydroquinolines: Asymmetric Synthesis of All C2–, C3– and C4–Functionalized Tetrahydroquinolines

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