In this review, the latest research progress in synthesis and application of variously decorated aromatic compounds possessing the indeno[2.1-c]fluorene scaffold is summarized. In addition to covering synthetic endeavors, their transformat...
Artikel
Rhodium‐Catalyzed (3+3) Cascade Cyclization of Diazobarbiturates with 2H‐Azirines for the Diastereoselective Construction of Spirooxazinopyrimidinediones
European Journal of Organic Chemistry, September 2025, DOI. Login für Volltextzugriff.
Von Wiley-VCH zur Verfügung gestellt
Under the catalysis of Rh2(esp)2 (10 mol%) and BINAP (20 mol%) in 1,2-dichloroethane at 80 °C, a (3+3) cascade cyclization between diazobarbiturates and 2H-azirines proceeds smoothly, yielding spirooxazinopyrimidinediones in 24–92% yield with >20:1 diastereoselectivity. The chemical structure of one compound has been confirmed by X-ray diffraction analysis, and the others are suggested by inference.
Under the catalysis of Rh2(esp)2 (10 mol%) and BINAP (20 mol%) in 1,2-dichloroethane at 80 °C, a (3+3) cascade cyclization between diazobarbiturates and 2H-azirines proceeds smoothly, yielding spirooxazinopyrimidinediones in 24–92% yield with >20:1 diastereoselectivity. The chemical structure of one compound has been confirmed by X-ray diffraction analysis, and the others are suggested by inference.
Zum VolltextÜberprüfung Ihres Anmeldestatus ...
Wenn Sie ein registrierter Benutzer sind, zeigen wir in Kürze den vollständigen Artikel.