We have developed a diastereoselective DMAP-catalyzed Michael addition of furanone (butenolide) to nitroalkenes. Notably, our method does not require the pre-activation of furanone as 2-(trimethylsiloxy)furan and utilizes water: ethanol as a solv...
Artikel
One‐Pot Tandem Alkylsulfonylation/Cyclization of Unactivated Alkenes to Construct Alkylsulfonyl‐Containing Polycyclic Quinazolinones Under Photocatalysis
Asian Journal of Organic Chemistry, August 2025, DOI. Login für Volltextzugriff.
Von Wiley-VCH zur Verfügung gestellt
Visible-light photoredox-catalyzed one-pot tandem alkylsulfonylation/cyclization of unactivated alkenes to construct alkylsulfonyl-containing polycyclic quinazolinones has been accomplished. This mild transformation affords the desired products in high compatibility of functional groups and easy scale-up.
Abstract
Visible-light photoredox-catalyzed one-pot tandem alkylsulfonylation/cyclization of unactivated alkenes to construct alkylsulfonyl-containing polycyclic quinazolinones from 4-alkyl Hantzsch esters, DABCO(SO2)2 and N-alkene-tethered quinazolinones has been accomplished. This mild transformation accommodates diversely decorated substrates, affords the target products in 69–90% yields, and can be readily scaled up. The efficacy of the current catalysis arises from the use of tetrabutylammonium decatungstate as the photocatalyst and cheap K2S2O8 as the oxidant.
Zum VolltextÜberprüfung Ihres Anmeldestatus ...
Wenn Sie ein registrierter Benutzer sind, zeigen wir in Kürze den vollständigen Artikel.