<p>A Ni(OAc)2 catalysed N-formylation of primary sulfonamides using gaseous carbon dioxide is reported. A range of aromatic, heteroaromatic, and aliphatic sulfonamides were formylated under ambient pressure of carbon dioxide in a closed system. This redox neutral method represents a mechanistically novel and operationally convenient method for employing carbon dioxide as a formyl equivalent.</p>

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Ni(OAc)2 Catalyzed N‐Formylation of Primary Sulfonamides Using Carbon Dioxide at Ambient Pressure

A Ni(OAc)2 catalysed N-formylation of primary sulfonamides using gaseous carbon dioxide is reported. A range of aromatic, heteroaromatic, and aliphatic sulfonamides were formylated under ambient pressure of carbon dioxide in a closed system. This redox neutral method represents a mechanistically...

<p>The readily available, modular and electronic circular dichroism (ECD)-silent derivatives of terephthalaldehyde (the probes) have exhibited an induced optical activity upon condensation with chiral primary amines. The central unit of the probe serves as an amine binder by forming imine bonds and is flanked by two extended chromophoric units (“the wings”). Modification of the wings by diphenylamine or carbazole units affects the sterical and spectroscopic properties of the probes. An increase in sterical congestion within the probe core resulted in a change in the mechanism of optical activity induction. In the more congested systems, the point-to-axial chirality transmission from the chiral amine (the inducer) to the chromophoric system led to the adaptation of helical conformation by “the wings” and the appearance of non-zero Cotton effects (CEs) in the low-energy part of the ECD spectrum. However, the sterically congested probes were sensitive to the chirality of the inducers but relatively indifferent to the differences in their structure. Thus, the chirality of the inducers triggers conformational change towards the thermodynamically preferred conformational diastereoisomer due to the probe's —1 - +1 operation scheme.</p>

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Ni(OAc)2 Catalyzed N‐Formylation of Primary Sulfonamides Using Carbon Dioxide at Ambient Pressure

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Point‐to‐axis optical activity induction in extended, sterically congested chromophoric systems

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