Ligand‐Free Copper‐Catalyzed Allenylative CP Coupling of Propargylic Acetates with H‐Phosphine Oxides

P Coupling of Propargylic Acetates with H-Phosphine Oxides"/>

A ligand-free CuTC-catalyzed allenylative CP coupling reaction of propargylic acetates with H-phosphine oxides to yield allenylphosphine oxides is reported, with scope and mechanism discussed.

The extra-ligand-free CuTC-catalyzed CP cross coupling reaction of propargylic acetates with H-phosphine oxides is reported to afford allenylphosphine oxides. The reaction took place efficiently with diphenylphosphine oxide and electron-deficient di(4-fluorophenyl)phosphine oxide, but less effectively with electron-rich ones such as di(4-methoxylphenyl)phosphine oxide and dialkylphosphine oxides. H-phosphine oxides themselves may serve as the ligand.

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