Für viele organische Mikroschadstoffe, insbesondere für die pharmazeutischen Wirkstoffe, stellt der Eintrag über das kommunale Abwassersystem den dominierenden Eintragspfad in die Umwelt dar. Keramische Membrantechnologie kann eine echte Alternat...

Artikel
Track‐Etched Membranes for Drug Pharmaceutical Research
Von Wiley-VCH zur Verfügung gestellt
Track-etched membranes serve as excellent support for cell growth and efficient nutrient supply, with the added benefit of precise control of pore parameters, a critical pre-requisite to achieve reproducible results. Here, we provide an overview of track-etched membrane technology in the context of applications in drug discovery and development.
Abstract
Over the last decades, the incorporation of membranes into micro physiological systems used for pharmaceutical research and drug development has grown significantly. One example is the use of microporous track-etched membranes in microfluidic systems like organs-on-a-chip and cell culture inserts for tissue engineering. Tissue-culture treated track-etched membranes serve as excellent support for cell growth and efficient nutrient supply, with the added benefit of precise control of pore parameters, a critical pre-requisite to achieve reproducible results. Here, we provide an overview of track-etched membrane technology in the context of applications in drug discovery and development.
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