Transition Metal‐Catalyzed C−H Functionalization Through Electrocatalysis

Merging transition metal catalysis with electrochemical oxidation has emerged as a potential catalyst system for C−H bond functionalization, avoiding the use of chemical-based oxidants. Electrochemically promoted electrooxidation of the metal catalyst offers a mild, efficient and atom-economical alternative to traditional chemical oxidant-based systems. This Review highlights recent advances in transition metal-electrocatalyzed C−H functionalization reactions.

Abstract

Electrochemically promoted transition metal-catalyzed C−H functionalization has emerged as a promising area of research over the last few decades. However, development in this field is still at an early stage compared to traditional functionalization reactions using chemical-based oxidizing agents. Recent reports have shown increased attention on electrochemically promoted metal-catalyzed C−H functionalization. From the standpoint of sustainability, environmental friendliness, and cost effectiveness, electrochemically promoted oxidation of a metal catalyst offers a mild, efficient, and atom-economical alternative to traditional chemical oxidants. This Review discusses advances in the field of transition metal-electrocatalyzed C−H functionalization over the past decade and describes how the unique features of electricity enable metal-catalyzed C−H functionalization in an economic and sustainable way.

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