Frontispiece: Aptamer‐LYTACs for Targeted Degradation of Extracellular and Membrane Proteins

Aptamers. In their Communication (e202218106), Zhi Zhu et al. report the development of aptamer-LYTACs (lysosome targeting chimeras) for the efficient degradation of the platelet-derived growth factor and the membrane protein PTK7 through the lysosomal degradation pathway.

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