Enantioselective Construction of Axially Iodobenzocarbazole Derivatives via Stereogenic‐at‐cobalt(III)‐complex‐catalyzed Iodoarylation of Alkynes

A new synthetic approach to novel axially chiral iodobenzocarbazole derivatives based on the highly enantioselective intramolecular iodoarylation of linked alkyne−indole systems was developed by using the versatile chiral catalyst, Stereogenic-at-cobalt(III) complex, through an axially chiral iodinated vinylidene o-quinone methide (IVQM) intermediate. This protocol provides 21 examples in excellent yields with good to high enantioselectivities (up to 96% yield, 98% ee). Furthermore, the introduced iodine atoms can easily be converted into other functional groups.