![Copper‐Catalyzed [3+2] Annulation of Pyridinium Ylides with α‐CF3 Ketones: Synthesis of Functionalized 2‐Fluoroindolizines](https://onlinelibrary.wiley.com/cms/asset/a8e2b2e2-c705-4247-b172-238056920128/ajoc202300075-toc-0001-m.png)
A copper-catalyzed [3+2] annulation of the in situ generated pyridinium ylides with α-CF3 ketones was realized, in which α-CF3 ketones first acted as the synthetic equivalents of unstable fluoroalkynones. With ...
Artikel
2,3′‐Bisindole Synthesis from o‐(2.2‐Dibromovinyl)aniline and o‐Ethynylaniline
Von Wiley-VCH zur Verfügung gestellt
Palladium catalysis: A Pd-catalyzed coupling reaction from o-alkynylanilines and o-(2,2-dibromovinyl)anilines for the synthesis of 2,3′-bisindoles is developed. The protocol exhibits high efficiency, good functional group tolerance and scalability from easily accessible starting materials
Abstract
A Pd-catalyzed coupling reaction from o-alkynylanilines and o-(2,2-dibromovinyl)anilines for the synthesis of 2,3′-bisindoles is developed. In which, o-ethynylaniline was used as 3-functionalized indole precursor and o-(2,2-dibromovinyl)aniline was used as 2-functionalized indole precursor. This protocol exhibits high efficiency, good functional group tolerance and scalability from easily accessible starting materials.
Zum VolltextÜberprüfung Ihres Anmeldestatus ...
Wenn Sie ein registrierter Benutzer sind, zeigen wir in Kürze den vollständigen Artikel.